{"id":264,"date":"2019-08-02T15:19:00","date_gmt":"2019-08-02T06:19:00","guid":{"rendered":"https:\/\/kamiuchidm-clinic.com\/blog\/?p=264"},"modified":"2021-03-20T15:20:36","modified_gmt":"2021-03-20T06:20:36","slug":"ukpdsuk-prospective-diabetes-study3334","status":"publish","type":"post","link":"https:\/\/kamiuchidm-clinic.com\/blog\/?p=264","title":{"rendered":"UKPDS(UK Prospective Diabetes Study)33,34"},"content":{"rendered":"\n

DCCT\u306f\uff11\u578b\u7cd6\u5c3f\u75c5\u304c\u5bfe\u8c61\u3067\u3057\u305f\u304c\u3001UKPDS\u306f\uff12\u578b\u7cd6\u5c3f\u75c5\u3092\u5bfe\u8c61\u306b\u884c\u308f\u308c\u30011998\u5e74\u306b\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002DCCT\u3068\u540c\u3058\u304f\u7cd6\u5c3f\u75c5\u5c02\u9580\u533b\u3067\u3042\u308c\u3070\u3060\u308c\u3067\u3082\u77e5\u3063\u3066\u3044\u308b\u30d0\u30a4\u30d6\u30eb\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002
\uff12\u578b\u7cd6\u5c3f\u75c5\u306e\u7d4c\u53e3\u8840\u7cd6\u964d\u4e0b\u85ac\u3067\u3042\u308bSU\u5264\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f7f\u7528\u3057\u53b3\u683c\u306b\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u305f\u7fa4\uff08\u5e73\u5747HbA1c 7.0%\uff09\u3068\u98df\u4e8b\u904b\u52d5\u7642\u6cd5\u304c\u57fa\u672c\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u305f\u7fa4\uff08\u5e73\u5747HbA1c 7.9%\uff09\u306b\u5206\u3051\u306610\u5e74\u304b\u3051\u3066\u5408\u4f75\u75c7\u9032\u884c\u5ea6\u3092\u307f\u307e\u3057\u305f\u3002\u53b3\u683c\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u305f\u7fa4\u3067\u306f\u7d30\u5c0f\u8840\u7ba1\u75c7\u306e\u767a\u75c7\u9032\u5c55\u304c\u6291\u5236\u3055\u308c\u307e\u3057\u305f\u304c\u3001\u5927\u8840\u7ba1\u75c7\u3067\u306f\u6291\u5236\u3092\u8a8d\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002(UKPDS33)\u3055\u3089\u306b\u3001\u80a5\u6e802\u578b\u306e\u65b9\u5bfe\u8c61\u3067\u85ac\u7269\u306b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3092\u4f7f\u7528\u3057\u305f\u5834\u5408\u306b\u304a\u3044\u3066SU\u5264\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f7f\u7528\u3057\u305f\u5834\u5408\u3068\u6bd4\u3079\u3066\u3001\u7cd6\u5c3f\u75c5\u95a2\u9023\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3001\u7dcf\u6b7b\u4ea1\u3001\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002(UKPDS34)<\/p>\n\n\n\n

\u3053\u306e\u7d50\u679c\u3067\u3001\u5206\u304b\u3063\u305f\u3053\u3068\u306f<\/p>\n\n\n\n

\uff11\uff092\u578b\u7cd6\u5c3f\u75c5\u3067\u3082\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u7d30\u5c0f\u8840\u7ba1\u75c7\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u3002<\/p>\n\n\n\n

\uff12\uff0910\u5e74\u9593\u306e\u7d50\u679c\u3067\u306f\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u660e\u3089\u304b\u306a\u5927\u8840\u7ba1\u75c7\u306e\u30ea\u30b9\u30af\u306f\u4e0b\u3052\u306a\u304b\u3063\u305f\u3053\u3068\u3002<\/p>\n\n\n\n

\uff13\uff09SU\u5264\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u6cbb\u7642\u3088\u308a\u3082\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3067\u5927\u8840\u7ba1\u75c7\u30ea\u30b9\u30af\u304c\u5927\u304d\u304f\u4f4e\u4e0b\u3057\u305f\u3053\u3068\u3002<\/p>\n\n\n\n

\u7d30\u5c0f\u8840\u7ba1\u75c7\u306e\u30ea\u30b9\u30af\u306f\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u5927\u304d\u304f\u95a2\u4e0e\u3057\u307e\u3059\u304c\u3001\u5927\u8840\u7ba1\u75c7\u306f\u8840\u7cd6\u306e\u307b\u304b\u306b\u8840\u5727\u30fb\u8102\u8cea\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u91cd\u8981\u3067\u3059\u3002SU\u5264\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u6539\u5584\u3057\u306a\u3044\u306e\u3067\u5927\u8840\u7ba1\u75c7\u306b\u306f\u52b9\u679c\u7684\u3067\u306f\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u3002\u4e00\u65b9\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u6539\u5584\u85ac\u3067\u3042\u308b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u306f\u4f53\u91cd\u5897\u52a0\u3082\u306a\u304f\u5927\u8840\u7ba1\u75c7\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u306f\u305d\u308c\u307e\u3067\u4e73\u9178\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u306e\u30ea\u30b9\u30af\u3092\u61f8\u5ff5\u3057\u307b\u3068\u3093\u3069\u4f7f\u308f\u308c\u308b\u3053\u3068\u304c\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u3053\u306e\u7d50\u679c\u3067\u4e73\u9178\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u3082\u307b\u3068\u3093\u3069\u8d77\u3053\u3055\u306a\u3044\u3053\u3068\u304c\u308f\u304b\u308a\u3001\u4f7f\u7528\u6570\u304c\u5287\u7684\u306b\u5897\u3048\u3066\u3044\u3063\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n

UKPDS33,34\u306e\u65e5\u672c\u8a9e\u3067\u306e\u8aac\u660e\u6587\u306f\u3053\u3061\u3089<\/p>\n\n\n\n

http:\/\/diabetes.ebm-library.jp\/trial\/detail\/50018.html<\/a><\/p>\n\n\n\n

http:\/\/diabetes.ebm-library.jp\/trial\/detail\/50019.html<\/a><\/p>\n\n\n\n

(UK Prospective Diabetes Study (UKPDS) Group.: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352: 837-853. )<\/p>\n\n\n\n

(UK Prospective Diabetes Study (UKPDS) Group.: Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998; 352: 854-865. )<\/p>\n","protected":false},"excerpt":{"rendered":"

DCCT\u306f\uff11\u578b\u7cd6\u5c3f\u75c5\u304c\u5bfe\u8c61\u3067\u3057\u305f\u304c\u3001UKPDS\u306f\uff12\u578b\u7cd6\u5c3f\u75c5\u3092\u5bfe\u8c61\u306b\u884c\u308f\u308c\u30011998\u5e74\u306b\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002DCCT\u3068\u540c\u3058\u304f\u7cd6\u5c3f\u75c5\u5c02\u9580\u533b\u3067\u3042\u308c\u3070\u3060\u308c\u3067\u3082\u77e5\u3063\u3066\u3044\u308b\u30d0\u30a4\u30d6\u30eb\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002\uff12\u578b\u7cd6\u5c3f\u75c5\u306e\u7d4c\u53e3\u8840\u7cd6\u964d\u4e0b\u85ac\u3067\u3042\u308bSU\u5264…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-264","post","type-post","status-publish","format-standard","hentry","category-ebm"],"_links":{"self":[{"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=264"}],"version-history":[{"count":1,"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/264\/revisions"}],"predecessor-version":[{"id":265,"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/264\/revisions\/265"}],"wp:attachment":[{"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kamiuchidm-clinic.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}